Faculty

Dr. Khaled Al Kattan Alexander Kouzmenko
Professor of Molecular Biology
College of Science and General Studies
Alfaisal University
Riyadh, KSA

Email: akouzmenko@alfaisal.edu
Tel : +(966-1) 215-7732 office

Publications: (Recent)
Refereed journal papers:

Imai Y., Kondoh S., Kouzmenko A., Kato S. – Osteoprotective action of estrogens is mediated by osteoclastic estrogen receptor α. – Molecular Endocrinology 2010, In Press
Takada I., Kouzmenko A.P., Kato S. – WNT and PPARy signaling in osteoblastogenesis and adipogenesis. – Nature Review Rheumatology 2009, 5(8), 442-447.
Imai Y., Kondoh S., Kouzmenko A., Kato S. – Regulation of bone metabolism by nuclear receptors. – Mol. Cell. Endocrinol. 2009, 310(1-2), 3-10.
Takada I., Kouzmenko A.P., Kato S. – Molecular Switching of Osteoblastogenesis Versus Adipogenesis: Implications for Targeted Therapies. – Expert Opinion On Therapeutic Targets 2009, 13(5), 593-603.
Imai Y., Youn M.Y., Kondoh S., Nakamura T., Kouzmenko A., Matsumoto T., Takada I., Takaoka K., Kato S. – Estrogens Maintain Bone Mass by Regulating Expression of Genes Controlling Function and Life Span in Mature Osteoclasts. Ann. N.Y. Acad. Sci. 2009, 1173 (Suppl 1), E31-E39.
Suzuki E., Ito S., Sawatsubashi S., Shirode Y., Zhao Y., Yamagata K., Furutani T., Tanabe M., Kouzmenko A., Aigaki T., Tabata T., Takeyama K., Kato S. – Aberrant E2F activation by androgen receptor polyglutamine expansion mutants in SBMA neurotoxicity. – Proc. Natl. Acad. Sci. USA 2009, 106(10), 3818-3822.
Zhao Y., Takeyama K., Sawatsubashi S., Ito S., Suzuki E., Yamagata K., Tanabe M., Kimura S., Fujiyama S., Ueda T., Murata T., Matsukawa H., Shirode Y., Kouzmenko A.P., Li F., Tabata T., Kato S. – Co-repressive action of CBP on Androgen Receptor transactivation in pericentric heterochromatin in a Drosophila experimental model system. – Mol. Cell. Biol. 2009, 29(4), 1017-1034.
Tanabe M., Kouzmenko A.P., Ito S., Sawatsubashi S., Suzuki E., Fujiyama S., Yamagata K., Zhao Y., Kimura S., Ueda T., Murata T, Matsukawa H., Takeyama K., Kato S. – Activation of facultatively silenced Drosophila loci associates with increased acetylation of histone H2AvD. – Gene Cells 2008,13 (12), 1279–1288.
Murata T., Suzuki E., Ito S., Sawatsubashi S., Zhao Y., Yamagata K., Tanabe M., Fujiyama S., Kimura S., Ueda T., Matsukawa H., Kouzmenko A., Furutani T., Kuranaga E., Miura M., Takeyama K., Kato S. – RNA-Binding Protein Hoip Accelerates PolyQ-Induced Neurodegeneration in Drosophila. – Biosci. Biotechnol. Biochem. 2008, 79 (9), 2255-2261.
Kouzmenko A.P., Takeyama K., Kawasaki Y., Akiyama T., Kato S. – Ligand-dependent interaction between estrogen receptor α and adenomatous polyposis coli. – Genes Cells 2008, 13 (7), 723-730.
Kimura S., Sawatsubashi S., Ito S., Kouzmenko A., Suzuki E., Zhao Y., Yamagata K., Tanabe M., Ueda T., Fujiyama S., Murata T., Matsukawa H., Takeyama K., Yaegashi N., Kato S. – Drosophila arginine methyltransferase 1 (DART1) is an ecdysone receptor co-repressor. – Biochem. Biophys. Res. Commun. 2008, 371 (4), 889-893.
Kouzmenko A.P., Takeyama K., Kawasaki Y., Akiyama T., Kato S. – Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli.　Oncogene 2008, 27 (36), 4888-4899.
Memezawa A., Takada I., Takeyama K., Igarashi M., Ito S., Aiba S., Kato S., Kouzmenko A.P. – Id2 gene targeted crosstalk between Wnt and retinoid signaling regulates proliferation in human keratinocytes. – Oncogene 2007, 26 (35), 5038-5045.
Ohtake F., Baba A., Takada I., Okada M., Iwasaki K., Miki H., Takemasa S., Kouzmenko A., Nohara K., Chiba T., Fujii-Kuriyama Y., Kato S. – Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. – Nature 2007, 446 (7135), 562-566.
Kouzmenko A.P., Takeyama K., Ito S., Furutani T., Sawatsubashi S., Maki A., Suzuki E., Kawasaki Y., Akiyama T., Tabata T., Kato S. – Wnt/β-catenin and estrogen signaling converge in vivo. – J. Biol. Chem. 2004, 279 (39), 40255-40258.

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